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Storage & Stability

MOTS-C Storage & Stability: Cold Chain, Half-Life & Shelf Life

3 min readPublished 2025-09-24Quality Peptide USA Research

MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded in the 12S rRNA region of the mitochondrial genome. It is studied as a metabolic regulator with reported activity in skeletal muscle, adipose, and hepatic models.. This guide covers storage & stability for MOTS-C — written for laboratory researchers sourcing US-synthesized peptides from Quality Peptide USA.

Lyophilized Shelf Life

Sealed lyophilized MOTS-C stored at 2–8°C maintains potency through the expiration date listed on the certificate of analysis (typically 24–36 months from manufacture). Short transit exposure to room temperature during shipping does not meaningfully degrade lyophilized peptide — the vacuum-sealed solid form is highly stable. Once received, refrigerate promptly for long-term storage.

Reconstituted Solution Stability

Lyophilized: 2–8°C. Reconstituted: refrigerate, use within 30 days. Benzyl alcohol in bacteriostatic water provides bacteriostatic protection but does not extend chemical stability indefinitely. Investigators running multi-week protocols should plan their aliquoting strategy in advance.

Reported Research Half-Life

Reported in-vitro / preclinical half-life for MOTS-C: Short in circulation (research models) Half-life depends on study system — plasma, tissue culture media, and intact-animal models all yield different effective windows.

Cold-Chain Shipping by Quality Peptide USA

Every order of MOTS-C ships with insulated cold packaging for transit, dispatched from US facilities on the same day for orders placed before 2 PM EST. Tracking is provided on every shipment so research teams can plan receiving and cold-room storage.

Research Use Only

All content is for laboratory and in-vitro research contexts only. Not intended to diagnose, treat, or prevent any condition. Not for human or veterinary consumption.

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